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Baclofen is a medicine that is intended for increased muscle tone. Conditions, accompanied by increased muscle tone, may be related with the following diseases: multiple sclerosis, spinal cord diseases, including infectious, traumatic failure or degenerative, cerebral palsy, stroke, head injuries, meningitis, as well as in alcoholism.
Today it is possible to buy baclofen online and get the medicine for further effective treatment almost in any online shop, but only we have the most fast delivery and we entirely guarantee product quality as we follow all prescribed conditions of keeping and buy medicines only from licensed drugmakers. Before buying the baclofen we strongly recommend to consider its pharmacological properties, dosing, possible side effects and contraindications.
Baclofen is myorelaxant a central mechanism of action, it refers to the group of chloro-phenyl butyric acid. The medicine action is based on the reduction of skeletal muscle tone caused by failure of the spinal cord. The medicine reduces the amplitude of the tendon reflexes, it depressing effects on cutaneous reflexes and muscle tone. Baclofen has no effect on the processes of neuromuscular transmission. Before you buy baclofen online, you should learn the legal dosage. It is known that high doses of the drug may provoke depression of the central nervous system. Besides, doctors do not except the influence on supraspinal center. The drug is taken orally (by mouth), and then quickly absorbed in the gastrointestinal tract. It should be noted that baclofen is able to penetrate into many tissues, but through the physiological barrier between the circulatory system and central nervous system is only a small part of it.
At this stage of treatment the baclofen shows high efficiency. However, it has contraindications. For example, due to the fact that the medicine can penetrate the placenta and breast milk, its use is contraindicated in pregnant and breastfeeding. The use of the drug in this case is possible as the only way to save the mother's life. Baclofen is capable of binding to plasma proteins is about 30%. The accepted dose of the medicine of 15% is included in the metabolism by the liver, it is provided by a process of elimination the amino groups from of molecules. Baclofen is almost all excreted in the urine. The elimination half-life generally ranges from 2.5 to 4 hours. During 72 hours of receiving the body is almost completely cleared of the drug.
Dosage is determined individually, so before you buy baclofen online, you need to determine appropriate dosage depending on the degree of damage the spinal cord.
- For adult patients the optimal dose is 5 mg - 3 times a day, then the dosage is increased to get the necessary therapeutic effect. Keep in mind that the maximum daily dose should not exceed 100 mg.
- For patients older than 65 years, the increasing dosages is at risk of side effects, so it should be done as carefully as possible.
- The initial dose for children is 5 mg, taken to three times a day. The increasing the dosage is calculated individually based on the age and body weight.
However, before you buy baclofen online, you need to learn about the side effects, most of which are appeared in the central and peripheral nervous system. Side effects may appear itself as follows: drowsiness, gait disturbance, fatigue, apathy, confusion, euphoria, depression, convulsions, and others. Also there are possible failures of the digestive system: nausea, vomiting, diarrhea or constipation. Sometimes the failures of concern and organ systems, forming, accumulating and excreting urine: difficulty removing urine, urinary retention, enuresis. Besides, there is a decrease in blood pressure, muscle weakness, muscle pain. Among the contraindications of the drug should be noted: Parkinson's disease, psychosis, convulsions, pregnancy, lactation, epilepsy, renal failure, hypersensitivity, and others.
Regardless of contraindications and side effects of the baclofen shows high efficiency, which causes patients' desire to buy baclofen online. However, the purchase of drugs, including baclofen, should be from reliable suppliers, medicines must be stored according to all rules and regulations. Our company guarantees the selling of high quality medicines! If you want to buy baclofen uk - go to page. We offer: buy and assess!